Most people envision bone as being uniformly solid, however nothing could be farther from the truth. Because that one thing, as you will certainly see later on in this section, bones come in many different shapes?long, short, flat, irregular, wormian, and also sesamoid?which have actually much in common, despite their differences. A typical bone can be damaged down into multiple parts, each with a details function:

Epiphysis. This component is at the extreme ends of the bone (epi = above), wherein joints (articulations) form. Diaphysis. The obelisk of a lengthy bone, i m sorry is the direction in ~ which the bone can withstand the most stress. Metaphysis. The metaphysis is the location where the diaphysis meets the epiphysis. This is where significant bone expansion occurs, and where blood start the bone. Periosteum. A slim membrane that covers the exterior of the bone, whereby tendons and ligaments affix to the bone. The external fibrous layer is whereby blood vessels, nerves, and also lymphatics attach to the bone, while the within osteogenic layer has actually bone cells important for the growth and repair of bone. Medullary (or marrow) cavity. This hollow cavity, in the diaphysis, is for the storage of yellow marrow. Endosteum. This membrane lines the medullary cavity, and also contains osteoprogenitor cell (unspecialized bone cells, together you will quickly see).

Up, Down, and Middle

As you have the right to see in number 5.1, the column of a long bone is referred to as the diaphysis. The central, fat-storing marrow cavity is found inside the diaphysis. At each finish of the bone, at the website of the synovial joint, is an area called epiphysis. At the juncture in between the two is one area referred to as the metaphysis.

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Figure 5.1The numerous parts of a usual long bone. The example shown here is a femur. (2003

The huge Picture

A specific pituitary disorder entails the overproduction of human development hormone, or hGH. In a child, this results in gigantism, vice versa, too tiny hGH outcomes in one type of dwarfism (other forms are led to by either extreme malnutrition or, in the situation of achondroplasia, a dominant gene). As an adult, as result of the formation of the epiphyseal line, the bones of the face, hands, and also feet will enlarge dramatically. This condition, i beg your pardon is watched in particular movie villains, is dubbed acromegaly.

Remember the organs, consisting of bones, require three connections: blood vessels (both arteries and veins), lymphatics, and also nerves. This structures go into the bone through small holes referred to as foramina. A hole particularly for blood vessels is dubbed a nutrient foramen (the singular form of foramina). Any kind of student deserve to tell if a skeleton is real by simply searching for foramina about the metaphysis. One more clue is the weight: real bones room lighter than solid models, due to the openings because that red and also yellow marrow.

Beyond the entering and exiting nerves and vessels, the metaphysis is likewise the location of the epiphyseal plates, which room the primary growth centers that a lengthy bone. There are four zones in the epiphyseal plate. The ar of relaxing cartilage is not associated in growth, yet it does anchor the plate to the remainder of the bone. The zone that proliferating cartilage and also zone the hypertrophic cartilage room both affiliated in developing chondrocytes (cartilage cells), however the latter zone is where maturation of the cell occurs. The last zone, whereby the bone in reality forms, is known as the zone the calcified cartilage.

As we age, the epiphyseal plates, which room less thick than bone and show up darker on one X-ray, will ossify (turn to bone), at which point they will show up as a light heat (called the epiphyseal line). This clues the finish of a bone"s ability to flourish longer; this ossification is usually finish by the at an early stage to mid twenties (although the sternum doesn"t complete until after ~ 30). The facial bones, and often the hands and also feet, however, carry out not avoid growing, which explains why a young Jimmy Stewart looked very different than he did as an old man.

The Harder they Come

Compact bone is noteworthy for the wide spacing that the cells within a tough crystal procession (see number 5.2). You may remember the both large spacing and also a procession were qualities of connective tissue. The main attribute of compact bone is its strength. It gives protection because that places external a soft structure, such as in the level bones the the skull. Compact bone additionally supports the stress put on it. In a lengthy bone, the anxiety is best soaked up along the longitudinal axis that the diaphysis. This setup is an excellent for a bone like the femur, i beg your pardon absorbs stress and anxiety in that direction, but the same cannot be claimed for the clavicle, which can be easily broken if that receives a downward blow perpendicular come the diaphysis.

Microscopically, compact (or dense) bone is identified by its setup of osteocytes (bone cells) in concentric circles of matrix. Simply as people settle about sources of water, these rings, or concentric lamellae, room arranged around a central haversian canal, which holds blood vessels. The combination of the concentric lamellae and the haversian canal is referred to as an osteon, or haversian system. In enhancement to the haversian canal, there space perpendicular ones dubbed perforating canals that affix haversian canals, and assist to carry out blood not just to the depth haversian systems, but additionally to the marrow cavity.

The osteocytes look a little like ants due to the fact that of the setup of tiny canals referred to as canaliculi about each cell; this canaliculi, who name constantly makes me think of an Italian dessert, space where the interstitial liquid is found. Canaliculi prolong outward in every direction from the lacuna, i m sorry is the space where the osteocyte is found.

Figure 5.2This is a diagram of haversian systems in compact bone. Note the company of the bone is based on the place of blood vessels. (LifeART1989-2001, Lippincott Williams & Wilkins)

Not simply For Mopping up Spills

Spongy or cancellous bone is very different in appearance. Quite than strictly concentric systems, spongy bone looks, well, spongy. The illustration is due to an irregular arsenal of overlapping and also interconnected spokes referred to as trabeculae (refer to figure 5.2). To know the duty of spongy bone, note that it shows up most frequently in the epiphysis, just under a security compact layer. The compact layer gives firm attachments for the articular cartilage, both that which aid to defend from the friction uncovered in every synovial joint.

So why the spongy part? In state of tension at the joint, imagine jumping in the air and landing tough on your feet while keeping your foot straight; a good deal of anxiety will it is in felt not only in her knees, but also where your femur articulates with your pelvis, no to mention in your back. Girlfriend can easily reduce the anxiety by bending your knees and also ankles; together bending absorbs the tension of the impact. Now do you recognize the factor for spongy bone? That"s right, come absorb several of the shock of affect at synovial joints.

The screwy multidirectional trabeculae make it possible to absorb stress and anxiety from multiple directions. In addition, the spaces in between the trabeculae do spongy bone lot lighter, for this reason making the skeleton together a whole much lighter. This spaces serve an additional purpose; they space filled v red bone marrow, the site of hemopoiesis.

Excerpted from The complete Idiot"s overview to Anatomy and also Physiology 2004 through Michael J. Vieira Lazaroff. All rights reserved including the appropriate of reproduction in whole or in part in any form. Provided by arrangement with Alpha Books, a member of Penguin group (USA) Inc.

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